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Depends on the guitar. I have 6 guitars with PAF's. some stay dialed wide open, some down around 4, some around 7-8. It all depends on the guitar & the tone I am looking for. Typically, I like the rolled back honk, but that can be found at different numbers on the tone knob.
disclaimer - not having PAFs but some good PAF clones, so ignore if OP question is strictly PAF related
While every guitar with PAFs (clones) has it's own sweet spot, I tend to set my whole rig to have the tone I'm satisfied with - neck on 6-8 with 15nF and bridge on 4-6 with 22nF, both clean tones and dirty ones. Each will still have it's own thing going, but I want them all in the ballpark that is mine.
If I have to go out of these ranges, it's time for modding, electrics or hardware or both. And if modding fails, it's not a LP for me.